Miguel and Peter Parker, the Spider-Man of the Heroic Age, find themselves having switched places, with Miguel waking up next to Peter's wife, Mary Jane, and Spider-Man finding himself in the future. They discover that their predicament is caused by Fujikawa (in the Modern Age) and Alchemax (in the year 2099) running experiments on a temporal energy generator. While Peter tackles the Vulture of 2099, Miguel faces Venom (Eddie Brock). Miguel realizes that this temporal anomaly is what will cause the end of the Heroic Age, since where he is in the past is when history tells him all the heroes and much of Earth's culture and technology were wiped out.
Soon, a time-traveling female Hobgoblin of the year 2211 (Robin Borne) from the alternative universe of Earth-9500. They are aided by this Hobgoblin's father, Spider-Man (Max Borne), and eventually everyone is sent back to their respective times.
- In this issue the event that led to the end of the Heroic Age has been averted, thus making 2099 rather an alternate future.